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CD147 anticorps

Cet anticorps Souris Monoclonal détecte spécifiquement CD147 dans WB, FACS, IF, IP et IHC (p). Il présente une réactivité envers Humain et a été mentionné dans 1 publication.
N° du produit ABIN119254

Aperçu rapide pour CD147 anticorps (ABIN119254)

Antigène

Voir toutes CD147 (BSG) Anticorps
CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Reactivité

  • 199
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  • 60
  • 17
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
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  • 1
Humain

Hôte

  • 125
  • 98
  • 9
  • 1
Souris

Clonalité

  • 158
  • 70
  • 4
Monoclonal

Conjugué

  • 107
  • 15
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  • 4
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  • 1
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Cet anticorp CD147 est non-conjugé

Application

  • 137
  • 110
  • 88
  • 69
  • 41
  • 41
  • 30
  • 22
  • 14
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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

MEM-M6-1
  • Specificité

    This antibody recognises the CD147 cell surface antigen.

    Purification

    Affinity Chromatography on Protein G

    Immunogène

    CD147Rg, consisting of the cDNA coding for the hinge region, CH2 and CH3 domains of Human IgG1.

    Isotype

    IgG1
  • Indications d'application

    Flow cytometry: 1/50 - 1/100, use 10 μL of the suggested working dilution to label 10^6 cells. Immunoprecipitation. Western Blot: under non-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    PBS, pH 7.4, 0.09 % Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Schneiderhan, Scheler, Holzmann, Marx, Gschwend, Bucholz, Gress, Seufferlein, Adler, Oswald: "CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models." dans: Gut, Vol. 58, Issue 10, pp. 1391-8, (2009) (PubMed).

  • Antigène

    CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

    Autre désignation

    CD147

    Sujet

    CD147 is a 50-60kD glycoprotein also known as neurothelin and basigin. CD147 is broadly expressed on peripheral blood cells and by endothelial cells. Expression upon T cells is increased following activation.Synonyms: 5F7, BSG, Basigin, Collagenase stimulatory factor, EMMPRIN, Extracellular matrix metalloproteinase inducer, Leukocyte activation antigen M6, OK blood group antigen, TCSF, Tumor cell-derived collagenase stimulatory factor

    ID gène

    682

    NCBI Accession

    NP_001719

    UniProt

    P35613

    Pathways

    S100 Proteins
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